18/02/2025
This is a study on the antiviral activity of ClO₂ against AIV and IBV.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10600528/
IBV and AIV both cause significant economic losses in the poultry industry. The key to IBV lies in its unique infectivity and its ability to spread via aerosols from infected chickens or contaminated equipment and materials. While IBV infections do not cause fatal diseases, they are extremely harmful to poultry farmers because it is known to lead to reduced productivity.
Currently, attenuated live vaccines are widely used to prevent IBV infections. However, the extreme variability and rapid evolution of IBV have become barriers to controlling infections through vaccination alone.
On the other hand, in Japan, the spread of highly pathogenic avian influenza (HPAI) is not prevented by vaccination, but by culling all chickens on farms that test positive for HPAI. During the 2022 to 2023 season, over 17 million chickens were culled due to HPAI outbreaks. One of the key measures to prevent and control highly pathogenic avian influenza outbreaks is improving sanitary conditions, as one of the major risks of avian influenza transmission is the poultry supply chain.
Additionally, surface disinfection is crucial because studies have shown that viruses can survive on surfaces for days or even months. In fact, research has found avian influenza on various surfaces of infected poultry farms. One study showed that avian influenza was detected inside, outside, and downwind of infected duck and chicken farms in France. To prevent infectious bronchitis and avian influenza infections in poultry farms, it is important to use disinfectants at the proper concentration and apply them in the right manner (e.g., on surfaces and in the air) to effectively reduce primary or residual viral contamination.
The experimental results show that low concentrations of liquid ClO₂ are sufficient to inactivate both AIV and IBV in water.
For suspension and carrier tests, virus suspensions containing 0.5% or 5% FBS were used to simulate the organic conditions of poultry farms. Previous research has indicated that the presence of organic matter does reduce the antiviral effectiveness of chlorine-based disinfectants. However, in contrast to these studies, even with the presence of 5% FBS, 10 ppm liquid ClO₂ showed adequate antiviral activity. This particularly suggests that, compared to other chlorine-based disinfectants, chlorine dioxide is less affected by organic matter.
The antiviral activity of chlorine dioxide (ClO2) in liquid (ClO2 gas dissolved liquid) and gaseous state against avian influenza virus (AIV) and infectious bronchitis virus (IBV) was evaluated. To evaluate the effect of ClO2 in liquid state, ...
