10/16/2026
You cannot strengthen a muscle your nervous system is protecting.
We see this all the time. A client has knee pain, their quads are weak, so they get a strengthening program.
They do the exercises for weeks and the quads are still weak. Then everyone decides they need to work harder, or maybe they failed to do their homework.
The muscle isn't the problem. The nervous system is reducing the drive to it.
When a joint is painful or irritated, the nervous system inhibits the muscles around it. It's protective, and it has a name…arthrogenic muscle inhibition. The muscle is fully capable, the nervous system just won't give you access to all of it.
The crazy thing is it doesn't take much to flip that switch.
When researchers made a healthy knee painful with a saline injection, strength dropped 5 to 15% right away, and the more it hurt, the weaker people got.
In another study, just 30 mL of fluid in a healthy knee inhibited the quads for at least two hours.
So if the nervous system has the brakes on, loading harder won't get you there. You're pushing the gas with the parking brake on.
What we do know? Only nociceptors can send the message. Treat the nociceptors and often the pain disappears, and when the pain goes, the strength very often comes back right there in the session.
Same muscle, same day.
Take the brakes off first. Then load it, and the strengthening actually has something to work with.
This is exactly what we teach in class.
Read more here. ⬇️
Henriksen et al., J Pain, 2011 | Hopkins et al., Med Sci Sports Exerc, 2001 | Rice & McNair, Semin Arthritis Rheum, 2010