04/20/2026
Great read from our friends at Diamond C Livestock!!!
There's been some significant conversation online lately about the use of Draxxin KP in sheep. If you Google, use AI, or even talk to most vets... beyond the fact it is not labeled for sheep (what is? 🙄) there is some pretty inconclusive advice out there.
🚨We're not vets but we and customers of ours have absolutely lost sheep to allergic reactions to Draxxin KP.🚨
After talking with experts, Zoetis, and doing a good bit of research we’ve learned some critical safety information:
1️⃣ Draxxin KP is NOT for Sheep
While standard Draxxin is a staple for foot rot and pneumonia, Draxxin KP (the combination with Ketoprofen, a nonsteroidal anti-inflammatory) is only labeled for cattle. The "KP" component hasn't been proven effective in sheep, and more importantly, the carrier/excipient used to stabilize the medication (likely polyethylene glycol) can trigger violent, often fatal, allergic reactions in sheep.
2️⃣ Dexamethasone will not save you
If a sheep has a reaction to Draxxin KP, your instinct might be to reach for dexamethasone to stop the reaction. STOP. 🛑
Standard dexamethasone often uses the same type of carrier (PEG) as Draxxin KP. It can actually worsen the anaphylaxis instead of fixing it.
3️⃣ Have epinephrine ready
No matter what you are injecting, whether it be vaccines, antibiotics, or otherwise, anaphylaxis can happen. Epinephrine and a fresh syringe should be kept close at hand. It is likely the only thing that can save them when a reaction hits.
We’re sharing this because we don’t want anyone else to go through the losses we (and others we know) have experienced. Please double-check your med cabinet and talk to your vet about the carriers in the drugs you use!
